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Machine learning and multi-omics data reveal driver gene-based molecular subtypes in hepatocellular carcinoma for precision treatment

Fig 2

Identification of driver gene-related subtypes.

(A) Flowchart depicting the process of the subtype classification algorithm; (B) Silhouette coefficients for different values of k; (C) Silhouette plot specifically for k = 2; (D) Heatmap of the consensus matrix defining the two subtypes; (E) Five-year survival curves for the two subtypes, with CLASS A represented in red and CLASS B represented in blue.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1012113.g002