Inferring fungal growth rates from optical density data
Fig 2
Logistic-OD model fit to OD600 data and estimated growth rates.
Posterior predictive distribution of the Logistic-OD model fit to the OD600 data (black dots) with (a) all the initial fungal inoculums (0, 1, 101, 102, 103 [N/μl], left to right) and (b) only the high fungal inoculum (103 [N/μl]). Solid lines and shades are medians and 95%, 80%, 60% credible intervals, respectively. The y-axes are in the log10 scale. (c) Hyphal growth rates (reference rates, green) estimated using a logistic model fit to direct data (Logistic-HL fit to hyphal length and Logistic-NC fit to nuclear count data, respectively) and those inferred from the Logistic-OD model fit to the indirect OD600 data, either all data (Logistic-OD) or only the data with high fungal inocula (Logistic-OD (High initial condition (IC))). Medians (dot), 95% (thin line) and 80% (thick line) credible intervals are shown. The hyphal growth rates of the Logistic-OD model are distinctly lower than the reference growth rates. All the inferred growth rates are shown on log10 scale.