Interpretable online network dictionary learning for inferring long-range chromatin interactions
Fig 10
Pairwise coexpression of genes covered by (a) the R1-R4 genomic regions, (b) the T1-T4 genomic regions, (c) an online cvxNDL dictionary element, and (d) a randomly constructed dictionary element.
We calculated the mean and standard deviation of absolute pairwise coexpression values, and the mean and standard deviation of coexpression values specifically for all positively correlated gene pairs. The mean coexpression values within TADs and dictionary elements are similar to each other and generally higher than those of randomly constructed dictionary elements. The x and y axis index genes that belong to the respective TAD regions or a specific dictionary element. Note that the plot (b) is of coarser resolution due to the small number of genes covered when compared to the cases (a), (c), (d).