Interpretable online network dictionary learning for inferring long-range chromatin interactions
Fig 6
Dictionary elements for Drosophila chromosome chr2L generated by (A) NMF, (B) online NDL, (C) CMF and (D) online cvxNDL.
NMF and CMF are learned off-line, using a total of 20, 000 samples. Note that these algorithms do not scale and cannot work with larger number of samples such as those used in online cvxNDL. The color-coding is performed in the same manner as for the accompanying online cvxNDL results. Columns of the dictionary elements in the second row are color-coded based on the genome locations of the representatives. As biologically meaningful locations can be determined only via convex methods, the top row corresponding to NMF and online NDL results is black-and-white.