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Predicting organoid morphology through a phase field model: Insights into cell division and lumenal pressure

Fig 7

Sphericity.

(a) Sphericity of organoids at various values of the minimum cell division time t_d and lumen pressure . The brown region with a star marker, *, represents the zero lumen region. The black solid, dashed, and dotted lines are included as visual guides. The solid and dashed lines suggest regions of single and multi-lumen formations, respectively, while the dotted line provides a reference for distinguishing between star-shaped and monolayer cyst structures. (b-d) Time evolution of the sphericity at various values of t_d and . See their morphology in Fig 5d.

doi: https://doi.org/10.1371/journal.pcbi.1012090.g007