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Predicting organoid morphology through a phase field model: Insights into cell division and lumenal pressure
Fig 5
Lumen occupancy.
(a) Time evolution of the lumen occupancy at the various td and 
. (b) Time variation rate of lumen occupancy for the various values of the minimum cell division time td and lumen pressure 
. The black dashed line serves as a visual guide to indicate zero rate. The lumen occupancy increases and decreases with time to above and below the black dashed line, respectively. (c) Value of the lumen occupancy at the final state for the various td and 
. The black dashed line here corresponds to the one in (b), demonstrating regions of increasing and decreasing lumen occupancy. (d) Snapshot of each parameter set of (a). The number labels represent the class of the organoid morphology: (i) star-shape, (ii) monolayer cyst, (iii) branched multi-lumen, (iv) multilayer multi-lumen, (v) multilayer single-stable-lumen, and (vi) multilayer no-stable-lumen.
doi: https://doi.org/10.1371/journal.pcbi.1012090.g005