A mathematical model for the role of dopamine-D2 self-regulation in the production of ultradian rhythms
Fig 3
Local sensitivity of the simulated ultradian period.
Local period sensitivity analysis performed at the nominal period of 4.0 h using Eq (7); Nominal parameter values listed in Table 2. The period is in general most sensitive to parameters unique to the release loop, moderately sensitive to parameters shared by both feedback loops, less sensitive to parameters unique to the removal loop, and not sensitive to parameters not directly involved in DA feedback (β).