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PESSA: A web tool for pathway enrichment score-based survival analysis in cancer

Fig 2

Survival analysis feedback Kaplan–Meier curve.

Survival analysis of patients in the median-grouped TCGA-BLCA dataset using the gene set TGF-beta Receptor Activation Levels in Emt Epithelial to Mesenchymal Transition (TGF-beta Receptor Activation Levels in Emt Epithelial to Mesenchymal Transition) sourced from the Reactome database. The results from the TCGA-BLCA dataset indicate that BLCA patients with high levels of activation of the TGF-beta Receptor EMT-related gene set (TGF-beta Receptor Signalling in Emt Epithelial to Mesenchymal Transition) had significantly shorter OS times than patients with low levels of activation. Abbreviations: BLCA: Bladder Cancer; OS: Overall Survival; TCGA: The Cancer Genome Atlas.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1012024.g002