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Clustering and visualization of single-cell RNA-seq data using path metrics

Fig 2

UMAP and PCA on Tabula Muris data sets.

Tabula Muris data sets have elongated clusters in the PCA embedding and clusters connected with a bridge of points in the UMAP embedding. For both PCA and UMAP embeddings, certain clusters are not well-separated and connected by high density regions.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1012014.g002