DBDNMF: A Dual Branch Deep Neural Matrix Factorization method for drug response prediction
Fig 8
Association of drug sensitivity with cancer gene mutations is consistent for predicted and existing responses.
A) RB1 mutated cell lines are more sensitive to the drug IOX2; B) RB1 mutated cell lines are more resistant to the drug Dactolisib; C) BARF mutated cell lines are more sensitive to the drug Refametinib.