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Bifurcations and bursting in the Epileptor

Fig 7

Role of x0 on the path.

A: A sketch of how, in hysteresis-loop bursting, x0 changes the position of the z-nullcline with regards to the resting state branch. B: When the intermediate subsystem is not allowed to oscillate (Irest2 = 0), different values of x0 do not change the path but only affect the velocities at which the slow variable evolves when the fast ones are in the interictal or ictal states. C: Allowing for intermediate oscillations to modulate the path (Irest2 > 0), changing x0 modifies the amount of spikes in the path (more spikes when the slow variable evolves slower while in the ictal state).

Fig 7

doi: https://doi.org/10.1371/journal.pcbi.1011903.g007