Computational models of compound nerve action potentials: Efficient filter-based methods to quantify effects of tissue conductivities, conduction distance, and nerve fiber parameters
Fig 9
Effect of bin size and sampling method on myelinated fiber CNAPs during extraction of fiber diameters from distributions.
(A) Histograms of known myelinated fiber diameters across different bin sizes. A bin size of 0 μm used the individual fiber diameter measurements (precision of 1e-6 μm). (B) Effect on CNAPs of generating fiber diameters based on the center of the bin and the bin height. As bin size increased, using the bin centers produced inaccuracies due to less destructive interference and more constructive interference. (C) Effect on CNAPs of generating fiber diameters based on inverse transform sampling to sample diameters randomly from the estimated cumulative distribution function. For a given non-zero bin size, CNAPs were more accurate than when using bin centers.