Tying the knot: Unraveling the intricacies of the coronavirus frameshift pseudoknot
Fig 5
Bat coronaviruses secondary structure predictions via KnotAli.
Top arc diagram: BtRf-BetaCov, free energy −43.24 kcal/mol, KJ473811, includes 3_6 motif. Bottom arc diagram: SARS-like WIV1-CoV, free energy −39.72 kcal/mol, KU444582, includes 3_3 motif. Mutations are indicated with red ovals. A △ symbol represents the mutation from the nucleotide on the left to the nucleotide on the right. Slippery sequence is highlighted in green and the downstream native pseudoknot target sequence in red.