Index analysis: An approach to understand signal transduction with application to the EGFR signalling pathway
Fig 13
Analyses of receptor degradation.
Comparison of the output ERK-PP and Raf* for the reference simulation (solid lines) and a modified model (dashed lines) with no degradation from six internalised receptor species (those with degradation reaction in Fig 9, realised by classifying the degradation products as cneg).