Index analysis: An approach to understand signal transduction with application to the EGFR signalling pathway
Fig 12
A: State classification indices for Raf*; B: comparison of the output ERK-PP and Raf* for the reference simulation (solid lines) and a modified model (dashed lines, visually indistinguishable from the solid lines) with Raf* in partial-steady state. C: State classification indices for Ras-GTP*; D: comparison of the output ERK-PP and Ras-GTP* for the reference simulation (solid lines) and a modified model (dashed lines) with partially neglected Ras-GTP* (pneg).