Pneumococcal population dynamics: Investigating vaccine-induced changes through multiscale modelling
Fig 2
Pre- and post-PCV7 population structure in four US states.
Each node represents a sequence type and each community (shaded patch) represents a serotype. Nodes are coloured according to the era of maximum sampled relative frequency, either pre- or post-PCV7. Communities are coloured according to whether or not the given serotype was a vaccine type (VT) or nonvaccine type (NVT). Edges represent a shared sequence type. Note that we include 6A as a vaccine type due to the effectiveness of PCV7 at targeting this serotype [17].