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Method to determine whether sleep phenotypes are driven by endogenous circadian rhythms or environmental light by combining longitudinal data and personalised mathematical models

Fig 9

Effect of light interventions.

The upper panels show one day of the original time series of the recorded light. The available light for the evening and the morning light intervention are shown in red / blue respectively. The bottom panels show the predicted sleep timing for each of the three cases (black, default; red, evening light reduction; blue, morning light enhancement). Predicted sleep timing is the average over a two week period starting two weeks after the beginning of the intervention.

Fig 9

doi: https://doi.org/10.1371/journal.pcbi.1011743.g009