Method to determine whether sleep phenotypes are driven by endogenous circadian rhythms or environmental light by combining longitudinal data and personalised mathematical models
Fig 2
Dependence of model predicted sleep duration and timing on model parameters and light exposure.
The top left panel shows two different light availability profiles. In all other groups of panels, the dependence of sleep duration (top panels), mid-sleep time (middle panels) and time of the circadian minimum (bottom panels) for the two light profiles are shown. The black vertical line indicates the default parameter values. Results are shown for all five sleep-wake parameters and five of the circadian-light parameters. The equivalent graphs for the remaining four circadian-light parameters are shown in Fig D in S1 Appendix.