Differences in boundary behavior in the 3D vertex and Voronoi models
Fig 6
(A) Representative image from a confocal z-stack from one Xenopus gastrula across the ectoderm-mesoderm boundary. Scale bar is 50 μm. (B) Example of manual tracing of projected cell shapes from this image. (C) Image illustrating calculation of center of mass (black dot) and best-fit ellipse (red ellipses) for cell shapes across the heterotypic interface. (D-E) Histograms of the average registration R for pairs of cells (D), and orientation O for all cells (E) in images from seven Xenopus gastrula. (F) Bar plot illustrating the average O and R in experiments (box with black and white lines), with an error bar representing the standard deviation. For comparison, the average O and R for the vertex (light magenta) and Voronoi (dark green) simulations across a broad physiological range of heterotypic interfacial tensions (between 0.1 and 1) is also shown, with the error bar representing the max and min values of those observed parameters in simulations for that range of tensions.