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How Merkel cells transduce mechanical stimuli: A biophysical model of Merkel cells

Fig 2

The membrane potential dynamics of one Merkel cell under the rectangular current pulses.

(A) Negetive current pulses step in 8.14pA (experimental current step in 10pA). (B) Membrane potentials change under negative current pulses. The solid lines are simulation results, and the triangles are experimental results from [21]. (C) Positive current pulses step in 8.14pA, Green line: 9 × 8.14pA, blue line: 14 × 8.14pA. (D) Membrane potentials change under positive current pulses. The solid lines are the simulation results, and the triangles are experimental results from [21]. The parameters of ion channels are seen in Table 3.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1011720.g002