Diffusive mediator feedbacks control the health-to-disease transition of skin inflammation
Fig 4
Pattern selection in the parameter space of pro- and anti-inflammatory mediator productions.
Fading (F), arcuate (Ar), polycyclic (P), gyrate (G), annular (An) and circular (C) patterns emerged as the steady state (Eq 2) at the parameter values of qa and pi (A), ra and qi (B). pa = 0.05, ra = 0.8, qi = 6.0 for (A) and pa = 0.05, qa = 3.0, pi = 0.12 for (B). In all the simulations, Da = Di = 0.3. (C) Summary for all the analyzed parameter space regarding the mediator production (see also S2 and S3 Figs), indicating the characteristic imbalance by each expanding pattern.