A cell-and-plasma numerical model reveals hemodynamic stress and flow adaptation in zebrafish microvessels after morphological alteration
Fig 4
Decrease in ISV diameter exacerbates the decrease in WSS caused by hematocrit reduction.
(A) Systolic WSS distributions in models WT (14% Ht), NoRBC1 (0% Ht) and NoRBC2 (0% Ht and 18% ISV diameter reduction). (B) Predicted systolic WSS levels in the CA (i), CV (ii), aISVs (iii) and vISVs (iv) for the 3 models. Statistical comparisons were performed using one-way ANOVA with Sidak’s multiple pair comparisons. **, p < 0.01; ****, p < 0.0001.