Understanding heterogeneous mechanisms of heart failure with preserved ejection fraction through cardiorenal mathematical modeling
Fig 6
Effect of HFpEF mechanisms on changes in LV end diastolic stress (A) vs. strain (B).
Reduced contractility, increased outward dilatation, and reduced arterial compliance caused both stress and strain to increase. However, increased LV stiffness caused them to change in opposite directions–stress increased while strain decreased.