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Information-theoretic analyses of neural data to minimize the effect of researchers’ assumptions in predictive coding studies

Fig 7

Spike-triggered averages (STAs) for spike tuples.

STAs for spike tuples with a silence time of 20 ms and inter-spike interval (ISI) up to 20 ms (aligned on first spike in a tuple). Left column shows lAIS values averaged over cell pairs for ISI of 1 ms to 10 ms, right column shows averaged lTE values (shaded areas indicate ±1SD). The lTE values are shifted by the individual delay between RGC and LGN cell for each pair such that a spike at index t = 0 indicates a transferred spike with a delay corresponding to the reconstructed information transfer delay. The predictability of the second RGC spike in a tuple, measured by the lAIS, was high for ISI from 3 ms to 7 ms, while first spikes in a tuple were unpredictable as indicated by no or negative lAIS. Information transfer measured by lTE was high for all RGC spikes with highest values for the second spike in a tuple.

Fig 7

doi: https://doi.org/10.1371/journal.pcbi.1011567.g007