Pervasive, conserved secondary structure in highly charged protein regions
Fig 2
Secondary structure is pervasive in highly charged, low complexity regions.
a The distribution of the fraction of a region predicted to be disordered with AlphaFold or present in DisProt. See Methods for secondary structure scoring. b The number of predicted helical, sheet, and disordered (which includes coil; see Methods) residues for the highly charged regions, randomly-selected regions, and experimentally verified disordered regions from DisProt. c (Left) The proportion of the top 200 most structured regions for which the protein that contains them is in the PDB. (Right) For those that are in the PDB, the proportion of regions that is a helix, sheet, or missing. d Uversky plot of the highly charged regions. The dividing line is from [2].