Spatial Configurations of 3D Extracellular Matrix Collagen Density and Anisotropy Simultaneously Guide Angiogenesis
Fig 2
Generation of collagen gels with varying anisotropy.
Collagen gels were aligned to low, moderate, and high anisotropy and imaged via second harmonic generation (SHG) in a prior study [1]. Image data was used to extract ODFs and fit EFDs for each level of alignment.