Mechanistic characterization of oscillatory patterns in unperturbed tumor growth dynamics: The interplay between cancer cells and components of tumor microenvironment
Fig 6
Models results and a graphical evaluation of the final tumor growth model: (A) visual predictive check: the black dots show the tumor volume measure, black lines represent the 5th, 50th and 95th percentiles of the raw data, colored areas denote the 95th confidence interval of model-predicted median (orange areas), 5th and 95th percentiles (blue areas). (B) Weighted residuals versus time (right panel) and lag plot (where i represents each residual value in chronological order of observations) (left panel). (C) Tumor volume vs time observations (solid circles) and individual model predictions corresponding to the individual model parameters obtained from the selected (orange) and Simeoni (blue) models, for six different mice chosen at random.