Tracking conformational transitions of the gonadotropin hormone receptors in a bilayer of (SDPC) poly-unsaturated lipids from all-atom molecular dynamics simulations
Fig 5
Principal component analysis for the LHCGR.
PC1 and PC2 (A-C) and PC3-PC4 (D-F) of trajectories R1-3 (blue dots). Projections for cluster 6383 of R1 (A, D), 4193 of R2 (B,E) and 2964 of R3 (C,F; black dots); clusters 2595 of R2 (B,E), and 1404 of R3 (C,F; lavender dots). TM domain conformations in clusters were identified with a 0.5 Å RMSD cutoff, ie. a structure was included whenever its RMSD was lower than 0.5 Å from any of the members in that cluster.