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Self-loops in evolutionary graph theory: Friends or foes?

Fig 8

Average extinction and fixation time for the self-looped directed line.

The average extinction time (dashed line) and the average fixation time (solid line) are shown for the self-looped directed line. Circles represent the total average time of the trajectories that lead to the fixation of mutants, whereas diamonds represent the average time spanned by the trajectories where mutants get extinct. We see a good agreement between analytical results and the corresponding simulations. The approximated formula for the average extinction time, Eq 82, works well in the regime of high relative fitness, as the dashed line starts coinciding with the simulations. Note that the average extinction time for a mutant can exceed the average fixation time. This is different from what we have observed in Figs 6 and 7. Also, for a given fitness domain, the average extinction and fixation time peaks away from the neutrality. Therefore, to decide the validity of the weak mutation rate approximation, fitness regions different from neutrality must be considered.

Fig 8

doi: https://doi.org/10.1371/journal.pcbi.1011387.g008