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Genome scale metabolic network modelling for metabolic profile predictions

Fig 5

Flux bounds (FVA) and distributions (sampling) for urate and hypoxanthine.

The WT state is shown in light blue, and the MUT state in red. MUT here corresponds to the knock-out of the XDH gene. Highlighted in grey, red, and dark blue are the absences of shifts (=), decreases (-), and increases (+) respectively between WT and MUT.

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1011381.g005