Genome scale metabolic network modelling for metabolic profile predictions
Fig 2
Methodology for the comparison of flux values and prediction of metabolite ranks.
Using a simple network (A) in two conditions (B), with single flux values (C). The methodology from Shlomi et al. [13] is shown in (D): each exported metabolite will have an associated change score for a given pair of conditions. (E) shows our methodology of scoring and ranking by absolute value among all of the metabolites in the network.