Identification of Low-Complexity Domains by Compositional Signatures Reveals Class-Specific Frequencies and Functions Across the Domains of Life
Fig 12
Comparison of secondary LCD distributions among eukaryotes.
(A) Distributions of secondary LCDs within primary LCD categories for all secondary LCDs identified in eukaryotic organisms. (B) Distributions of human secondary LCDs among primary LCD categories. (C) Distributions of yeast secondary LCDs among primary LCD categories. For all panels, secondary LCDs were grouped into a primary LCD category based on the predominant amino acid used in the LCD search. Then, within each primary LCD category, the percentage of total LCDs in that category was calculated for all possible secondary LCD categories and depicted as a stacked bar plot. For all secondary amino acid classes, the primary amino acid is represented on the x-axis, the bar color specifies the secondary amino acid, and the size of the bar indicates the percentage. Secondary amino acids are loosely grouped and colored according to physicochemical properties and appear in the same order (from bottom to top) as in the figure legends. Total LCD sample sizes are indicated above each bar.