A stochastic analysis of the interplay between antibiotic dose, mode of action, and bacterial competition in the evolution of antibiotic resistance
Fig 5
Mean carriage time of the resistant subpopulation in a host (including the treatment time τ = 7).
The carriage time is set to zero if the resistant subpopulation did not survive antibiotic treatment. Discontinuities are a result of discontinuities in the estimate of the resistant subpopulation size at the end of treatment (discussion in Section D in S1 Appendix). The theoretical predictions (lines) are derived in Section E. Symbols show the average carriage time of 106 stochastic simulations. The color coding and figure structure is the same as in the previous figures. Parameters are the same as in Fig 3.