Steady-state approximations for Hodgkin-Huxley cell models: Reduction of order for uterine smooth muscle cell model
Fig 7
Comparison results from Tong, 2011 Fig 11A, Fig 11B and Fig 11C and Tong, 2014 Fig 8D. Stimulus strength varied as noted aimed at reproducing experimental results (insets, Panels A-C) as given in Tong, 2011 Fig 11, or extended bursting (Panel D). Each Iapp applied up to t = 10 s starting at t = 1 s, except Panel D out to t = 50 s. Additional simulation with elevated extracellular initial condition K+ at 10 mM for comparison and no applied stimulus (blue dotted, Panel B). Conductances for key currents: gCaL = 0.6, gNa = 0.0895, gK1 = 0.7 pA/pF (identical to SSP values, Panels A-C), with gK1 = 0.75 for Panel D. Experimental traces (insets) adapted from Tong, et al. 2011 Fig 11.