Models of Purkinje cell dendritic tree selection during early cerebellar development
Fig 6
Change in path lengths with during simulation in retraction scenarios.
The plots show changes in max path length of candidate trees at every simulation cycle with a different line color for each tree. Three Purkinje cells were randomly selected from one of 20 simulations. Max path lengths of a tree drops to 0 when they are retracted. Some trees stop growing before the retraction phase, resulting in more shallow lines, for example blue line in A2. (A1-3) FixedRetract scenario. Since this scenario induces retractions at two fixed cycles, all retractions occur at either cycle 90 or 97. (B1-3) SizeRetract scenario. Similar plots as A1-3. Some cells skipped the first retraction because all the dendritic trees had a larger number of fronts than the threshold (20 fronts) when a cell reached the first retraction threshold (300 fronts), resulting in a single retraction event. (C1-3) SynapseRetract scenario. (D1-3) InputRetract scenario. Plots were generated by data using parameters as in Table 1, except D1 and D2 are from a parameter set with Whole_signal_1st = 10,000 and Whole_signal_2nd = 13,000.