Modeling suggests that virion production cycles within individual cells is key to understanding acute hepatitis B virus infection kinetics
Fig 5
HBV virion production (circles) and viral production cycles (triangles) in representative mouse (M1) inoculated with 108 HBV genome equivalents shown in Fig 3A. (A and B) represent infected cells with minimum eclipse phase of 9 hr (black-shaded “E”). (C and D) infected cells with maximum eclipse phase of 48hr. Similar predictions for mice M2, M3 and M4 are shown in Fig V in S1 Text.