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Effective mechanical potential of cell–cell interaction explains three-dimensional morphologies during early embryogenesis

Fig 6

Outcomes of simulations based on inferred distance–force curves.

A. Simulations results under the DF curves derived from C. elegans and mouse embryos are exemplified. B and C. DF curves sampled before reaching the minima of G, and simulation outcomes. DF curves, left panels; the values of G and the maximum attractive forces in the DF curves, right panels; simulation outcomes for each DF curve with the initial configuration ("start”), bottom panels. The values of G are relative to that in the case of all forces = 0. The colors in each three panels in B and C correspond each other. In the right panels, the numbers of the data points are 14 and 12 in B and C, respectively, and the representative ones (colored circles) are selected for presenting the DF curves and the simulation outcomes.

Fig 6

doi: https://doi.org/10.1371/journal.pcbi.1011306.g006