Implicit model to capture electrostatic features of membrane environment
Fig 8
Test4: ΔΔGins of polyleucines.
ΔΔGins is the energy difference between the lowest energy orientation of the peptide in the lipid bilayer phase and that in the aqueous phase. ΔΔGins is a measure of the affinity of a folded protein to be in the membrane phase relative to the aqueous phase. Predicted ΔΔGins are compared with experimental and values calculated by MD simulations.