A biologically inspired repair mechanism for neuronal reconstructions with a focus on human dendrites
Fig 8
Repairs restore the detailed electrophysiological behaviour of neurons.
Top, Example voltage traces of intentionally cut and subsequently repaired mouse CA1 pyramidal neuron current clamp simulations using the model by [65, 66] (neuron data by [68]). Reference in black, cut in magenta, repair in green (same colour scheme for the entire figure). A zoomed in version for the spiking traces is shown below for clearer visibility (zoom shows the beginning of the traces where spiking commences). Middle (left to right), Firing frequency, sag voltage and half width of the first spike plotted against stimulation current increments. Bottom (left to right), Interspike interval between the first and second spike, spike adaptation index and difference between the peak of the first and second spike plotted against stimulation current increments.