Cell to whole organ global sensitivity analysis on a four-chamber heart electromechanics model using Gaussian processes emulators
Fig 6
Simulated pressure-volume transients.
Top: LV pressure-volume transients and pressure traces simulated with the fully-coupled simulator (black), with the orange and the blue circles representing the resulting LV peak pressure and transient duration. The horizontal and the vertical lines show the clinically measured average LV peak pressure and transient duration, respectively, to show that the simulator achieves physiological values. Bottom: RV, LA and RA simulated pressure-volume transients.