< Back to Article

Enhanced perfusion following exposure to radiotherapy: A theoretical investigation

Fig 10

The impact of the mean diameter and the diameter heterogeneity on the perfusion response.

Series of plots (A–I) showing, for the forking network, the influence of the mean diameter () and the diameter heterogeneity (α) of the unpruned network on how perfusion () changes during pruning. An increase in the number of perfused vessels is evidence of flow being rerouted into vessels that were previously hypoperfused. An increase in without an increase in perfused vessels is evidence of Mechanism 2. Regions in which Mechanism 1 is primarily active are highlighted in grey.

doi: https://doi.org/10.1371/journal.pcbi.1011252.g010