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Enhanced perfusion following exposure to radiotherapy: A theoretical investigation

Fig 2

Representative vascular architectures from our experiments [15].

A single dose of 15 Gy X-rays was delivered to a tumour and changes to its vascular structure were monitored over the course of 4 days (reproduced from [50]). In the top row, endothelial cells are in cyan, while perfused vessels (qDot705) are in red. Every panel is a 2D representation of a 3D image in the form of a Z-stack approximately 300 μm tall. The depth of field for a single Z-slice was 2 μm. The middle and the bottom row show images of endothelial cells and perfused vessels, respectively. The scale bar corresponds to 100 μm.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1011252.g002