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A multi-scale clutch model for adhesion complex mechanics

Fig 9

Sensitivity analysis of the parameters integrin-fibronectin bond model.

Sensitivity analysis for the model parameters kont, koff,slip, koff,catch and Fb,slip = Fb,catch (a-d). We plot the variables Pb, the number of binders with vinculin (Bin. w/vinc), , and P against Young’s modulus of the substrate E in columns. The results are obtained averaging over 10 Gillespie simulations.

Fig 9

doi: https://doi.org/10.1371/journal.pcbi.1011250.g009