A multi-scale clutch model for adhesion complex mechanics
Fig 6
Computational results in an AC with α5β1 and αVβ3 integrins.
Results are averaged over 10 Gillespie simulations. We plot Pb, Bin. w/ Vinc., folding/unfolding states, xintmax and xtalinmax and Fcmax against Young’s modulus of the substrate E for ACs crowded with α5β1 (a) and αVβ3 (b). The color plot shows the folded/unfolded state of talin domains and it is obtained for one Gillespie simulation, averaging over the bound binders.