Dose optimization of an adjuvanted peptide-based personalized neoantigen melanoma vaccine
Fig 2
Patient-specific initial conditions are the values of all population variables in Table 1 at the start of the treatment. Patient-specific parameters are T cell recruitment and tumor killing rates, while neoantigen-specific parameters refer to unique immunogenic peptide sequences and binding affinities tailored to each patient. All these values can be found in Tables A and B in S1 Appendix.