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A dynamic calcium-force relationship model for sag behavior in fast skeletal muscle

Fig 5

Variation in the calcium-force relationship during isometric force production at X_m,0.5 for CAT14.

A. Steady-state relationship of muscle activation () to calcium binding troponin relative to the total troponin concentration (CaT/T₀) in the initial and maximally varied states at various stimulation frequencies. B. Transient relationship of muscle activation (A) to CaT/T₀ at various levels of stimulation frequency. C. Transient relationship of muscle force (F) and sarcoplasmic calcium (Ca) at various levels of stimulation frequency. Insets indicate the transient relationship between calcium and activation (B) and calcium and force (C) on the relaxation phase of force production.

doi: https://doi.org/10.1371/journal.pcbi.1011178.g005