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Amino acid sequence assignment from single molecule peptide sequencing data using a two-stage classifier

Fig 14

Performance on yeast.

The example shows 10K simulated reads from peptides derived from 100 proteins randomly selected from a yeast proteome, considering trypsin digestion and labels on D/E, C, and Y. We note the “HMM (no pruning)” curve is hidden under the “HMM (pruned)” curve.

Fig 14

doi: https://doi.org/10.1371/journal.pcbi.1011157.g014