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HaploCart: Human mtDNA haplogroup classification using a pangenomic reference graph

Fig 2

Performance on empirical paired-end FASTQ data.

Distribution of edit (Levenshtein) distances between assigned and underlying haplogroup of replicates from the empirical dataset. Central bars represent the arithmetic means of the distribution. For each window, HaploCart outperforms HaploGrep2 and HaploGrouper at all coverage windows as determined by the means of the distribution. It is worth noting that unlike HaploGrep2, HaploCart makes a prediction if even a single read maps to the graph.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1011148.g002