The proportion of resistant hosts in mixtures should be biased towards the resistance with the lowest breaking cost
Fig 4
Prevalence of the disease (P, black line) at equilibrium as a function of the proportion of resistance 2 (p), when varieties are not epidemiologically interchangeable (c1 ≠ c2).
(A) When priming occurs (ρ = 0.9), there is a unique optimal proportion biased towards the variety the most likely to be broken, here variety 1 (assumming c1 < c2). (B) In absence of priming (ρ = 0), the disease prevalence is minimized for a range of p values. The colored areas correspond to different genetic compositions of the pathogen population at equilibrium. From left to right: monovirulent 1 only, coexistence of monovirulent 1 and doubly virulent, doubly virulent only, coexistence of monovirulent 2 and doubly virulent, and monovirulent 2 only. Parameter values: R = 7, ν = 1, c1 = 0.1, and c2 = 0.4.