Canonical Response Parameterization: Quantifying the structure of responses to single-pulse intracranial electrical brain stimulation
Fig 9
Voltage deflections in the scalp EEG from intracranial sEEG electrical stimulation pulses, and automated artifactual trial identification.
A. Schematic, showing sEEG stimulation and EEG recording. B. Ten single-pulse EEG trials (gray) and average trace across trials (black). Note the clearly artifactual trial. C. Time-resolved projection magnitudes for trials from (B). D. Projection magnitudes at τR = 0.23s, suggesting that trial #6 is artifactual (p = 1.8⋅10−6, unpaired t-test comparing red+green vs black). Green dots indicate projections of normalized trial #6 into other trials, and red dots indicate normalized projections of other trials into trial #6. E and F. As in (B and C), with trial #6 removed. Note the change in τR from 0.23 to 0.28s and from 8.5 to 14.5μV
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